NSHD – Age 68-70 – ACE-III Memory
The MRC National Survey of Health of Development (NSHD) assessed their cohort members (CMs) during the study’s age 68-70 sweep using the Addenbrooke’s Cognitive Examination-III (ACE-III): Memory measure.
Details on this measure and the data collected from the CMs are outlined in the table below.
In this section
| Years of data collection: | 2014-2016 |
| Domain: | Verbal memory |
| Measures: | Memory |
| CHC: | Gc (Crystallised Intelligence) |
| Glr (long-term storage and retrieval) | |
| CLOSER Source: | Explore this sweep in CLOSER Discovery: NSHD 2014 (Age 68) and 2015 (Age 69) (links open in a new tab) |
| Administration method: | Administered by a research nurse. Mostly conducted using ACEmobile app, installed on an iPad, with prompts to guide interviewer through the process. Pen and paper used where necessary (e.g. drawing tests). |
| Procedure: | After the attention section was completed, participants were asked to recall the three words they were asked to remember (‘lemon’, ‘key’ and ‘ball’; 0 – 3). Participants were then asked to memorise an address consisting of 7 elements. They were given two practice trials, and a third trial took place later in the interview; this was the only trial that was scored (0 – 7). Those who remembered all 7 elements of the address were given an additional 5 points. Those who got at least one element of the address wrong were then given primers to help them recall the correct elements (0 – 5). They were then asked to name: (i) the current Prime Minister; (ii) the first woman who was Prime Minister; (iii) the USA president; (iv) the USA president who was assassinated in the 1960 (0 – 4). |
| Link to questionnaire: | https://skylark.ucl.ac.uk/NSHD/lib/exe/fetch.php?media=mrepo:ace-iii.pdf (opens in new tab) |
| Scoring: | One point per correct answer (0 – 26) |
| Item-level variable(s): | Not currently available |
| Total score/derived variable(s): | ACESCRMM15x |
| Descriptives: | Raw score |
| N = 1,787 | |
| Range = 7 – 26 | |
| Mean = 23.46 | |
| SD = 2.86 | |
(click image to enlarge) |
|
| Age of participants (months): | Mean = 834.14, SD = 2.93, Range = 828 – 848 |
| Other sweep and/or cohort: | None |
| Source: | Mathuranath, P. S., Nestor, P. J., Berrios, G. E., Rakowicz, W., & Hodges, J. R. (2000). A brief cognitive test battery to differentiate Alzheimer’s disease and frontotemporal dementia. Neurology, 55(11), 1613-1620. |
| Technical resources: | Noone, P. (2015). Addenbrooke’s cognitive examination-III. Occupational Medicine, 65(5), 418-420. |
| Example articles: | Matías-Guiu, J. A., Valles-Salgado, M., Rognoni, T., Hamre-Gil, F., Moreno-Ramos, T., & Matías-Guiu, J. (2017). Comparative diagnostic accuracy of the ACE-III, MIS, MMSE, MoCA, and RUDAS for screening of Alzheimer Disease. Dementia and Geriatric Cognitive Disorders, 43(5-6), 237-246. |
| James, S. N., Davis, D., O’Hare, C., Sharma, N., John, A., Gaysina, D., … & Richards, M. (2018). Lifetime affective problems and later-life cognitive state: Over 50 years of follow-up in a British birth cohort study. Journal of Affective Disorders, 241, 348-355. |